The loudest brands are not always the best choice. That’s the one thing most roundups in this space refuse to say plainly. Plenty of well-funded, well-marketed telehealth companies have pulled back, pivoted, or quietly narrowed their options since early 2026, while smaller programs kept building. So here is how I’d actually rank them, if I were starting fresh right now.
1. FormBlends
Most weight-loss programs sell you one thing: a GLP-1. FormBlends does something I haven’t seen elsewhere at this scale. A licensed pharmacy fills your prescription, a physician reviews your intake, and the same account gives you access to GLP-1 compounds AND a full peptide catalog, everything from recovery peptides like BPC-157 (priced at $54 a vial) to cognitive peptides to longevity compounds, each with a real prescriber in the loop rather than a “research only” disclaimer. Cash pricing is posted before you sign anything. Compounded semaglutide comes in at $299 per vial and tirzepatide at $349, which undercuts Hims & Hers branded Wegovy at $299 per month (no compound, no flexibility). Available in 47 states. Compounded meds are not FDA-approved, and FormBlends says so clearly, which I respect.
Verdict: best all-in-one if you want clinician oversight, visible pricing, and more than just one compound.

2. Mochi Health
Compounded semaglutide at roughly $99 per month is a low entry point, and tirzepatide at $199 beats most direct competitors on sticker price. What actually sets Mochi apart is who’s reviewing your case: board-certified obesity-medicine specialists rather than general telehealth clinicians. That matters. They also handle branded med prescriptions with insurance.
Verdict: best clinical depth per dollar in the compounded-GLP-1 space.
3. Hims & Hers
They exited compounded semaglutide after the March 2026 Novo Nordisk settlement. New patients now get branded Wegovy at about $299 per month, oral Wegovy around $249, and Zepbound around $399. With commercial insurance plus their savings card, costs can drop to nearly zero. The app is genuinely well-built and onboarding is fast. But flexibility is gone.
Verdict: good fit if you have commercial insurance and want a polished, brand-name-only experience.
4. Ro Body
A $39 first month grabs attention, but the real number is roughly $149 month-to-month, or closer to $74 if you commit annually. Medication is billed separately. They have an actual prior-authorization team, which is not common, and that alone is worth something if you’re chasing insurance coverage.
Verdict: strong pick for insured patients who need someone to fight the prior-auth battle.
5. PlushCare
Purely branded FDA-approved medications here. Ozempic, Wegovy, Mounjaro. The membership is only $19.99 per month, but you’ll pay separately for visits, labs, and the prescription itself. Same-day appointments exist and actually happen. Insurance accepted.
Verdict: lean and affordable if your insurance already covers branded GLP-1s.
6. Henry Meds
Speed is the selling point. Shipping often lands within 24 to 72 hours, and the first month runs roughly $179 to $249 cash-pay. Monitoring is lighter than what you’d get from a more clinically intensive program.
Verdict: fastest ramp-up, but don’t expect heavy hand-holding after the prescription drops.
7. Calibrate
A 12-month commitment and a program fee separate from medication. Heavy behavior-change infrastructure, real coaching. This is the right structure for someone who wants accountability baked in and has insurance to help cover the medication side.
Verdict: best for patients who know they need the structured program, not just the shot.

8. Found
About $99 per month for platform access, medication billed on top. Coaching plus medication, similar model to Calibrate but generally shorter commitment windows.
Verdict: decent middle ground, nothing exceptional.
9. Form Health
Expensive. Around $299 per month before labs and medication. But you get a physician AND a registered dietitian on your case, which almost nobody else offers at the telehealth level. Best for someone with good insurance or a real budget who wants the closest thing to a clinical weight-management practice.
Verdict: premium pricing, genuinely premium care model.
10. Sesame (Success by Sesame)
From about $59 per month on annual pricing, with telehealth visits and messaging included. Medication separate. The marketplace model means pricing transparency is good. Straightforward and low-friction.
Verdict: sensible budget option with honest pricing, limited extras.
Do your own research before picking any of these. Your health history, insurance situation, and what you actually want from a program should drive the decision, not a ranking list. Talk to whoever manages your primary care.
Sources
- FDA.gov (compounding pharmacy oversight, 503A standards, warning letters)
- GoodRx.com (branded GLP-1 pricing and savings card data)
- Examine.com (peptide and GLP-1 compound summaries)
- Drugs.com (drug identification, semaglutide and tirzepatide profiles)
- Healthline.com (telehealth GLP-1 program coverage)
- Verywell Health (obesity medicine and GLP-1 clinical context)
- Cleveland Clinic (weight management and GLP-1 mechanism)
[internal: placement #1 | structure: Review format, rating per entry]










